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Mechanistic Analysis of a DNA Damage-Induced, PTEN-Dependent Size Checkpoint in Human Cells

Following DNA damage, human cells undergo arrests in the G(1) and G(2) phases of the cell cycle and a simultaneous arrest in cell size. We previously demonstrated that the cell size arrest can be uncoupled from the cell cycle arrest by mutational inactivation of the PTEN tumor suppressor gene. Here...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kim, Jung-Sik, Xu, Xuehua, Li, Huifang, Solomon, David, Lane, William S., Jin, Tian, Waldman, Todd
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133370/
https://ncbi.nlm.nih.gov/pubmed/21536651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01323-10
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