Histone Deacetylase 6 and Heat Shock Protein 90 Control the Functions of Foxp3(+) T-Regulatory Cells

Foxp3(+) T-regulatory cells (Tregs) are key to immune homeostasis such that their diminished numbers or function can cause autoimmunity and allograft rejection. Foxp3(+) Tregs express multiple histone/protein deacetylases (HDACs) that regulate chromatin remodeling, gene expression, and protein funct...

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Main Authors: de Zoeten, Edwin F., Wang, Liqing, Butler, Kyle, Beier, Ulf H., Akimova, Tatiana, Sai, Hong, Bradner, James E., Mazitschek, Ralph, Kozikowski, Alan P., Matthias, Patrick, Hancock, Wayne W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133361/
https://ncbi.nlm.nih.gov/pubmed/21444725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05155-11
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