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IκB Kinase β Promotes Cell Survival by Antagonizing p53 Functions through ΔNp73α Phosphorylation and Stabilization

ΔNp73α, a dominant-negative inhibitor of p53 and p73, exhibits antiapoptotic and transforming activity in in vitro models and is often found to be upregulated in human cancers. The mechanisms involved in the regulation of ΔNp73α protein levels in normal and cancer cells are poorly characterized. Her...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Accardi, Rosita, Scalise, Mariafrancesca, Gheit, Tarik, Hussain, Ishraq, Yue, Jiping, Carreira, Christine, Collino, Agnese, Indiveri, Cesare, Gissmann, Lutz, Sylla, Bakary S., Tommasino, Massimo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133237/
https://ncbi.nlm.nih.gov/pubmed/21482671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00964-10
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