IκB Kinase β Promotes Cell Survival by Antagonizing p53 Functions through ΔNp73α Phosphorylation and Stabilization

ΔNp73α, a dominant-negative inhibitor of p53 and p73, exhibits antiapoptotic and transforming activity in in vitro models and is often found to be upregulated in human cancers. The mechanisms involved in the regulation of ΔNp73α protein levels in normal and cancer cells are poorly characterized. Her...

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Bibliografiske detaljer
Main Authors: Accardi, Rosita, Scalise, Mariafrancesca, Gheit, Tarik, Hussain, Ishraq, Yue, Jiping, Carreira, Christine, Collino, Agnese, Indiveri, Cesare, Gissmann, Lutz, Sylla, Bakary S., Tommasino, Massimo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133237/
https://ncbi.nlm.nih.gov/pubmed/21482671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00964-10
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