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Enzymatic and Mutational Analyses of a Class II 3′,5′-Cyclic Nucleotide Phosphodiesterase, PdeE, from Myxococcus xanthus
Myxococcus xanthus PdeE, an enzyme homologous to class II 3′,5′-cyclic nucleotide phosphodiesterases, hydrolyzed cyclic AMP (cAMP) and cGMP with K(m) values of 12 μM and 25 μM, respectively. A pdeE mutant exhibited delays in fruiting body and spore formation compared with the wild type when cultured...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133037/ https://ncbi.nlm.nih.gov/pubmed/21317337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01250-10 |
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