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Enzymatic and Mutational Analyses of a Class II 3′,5′-Cyclic Nucleotide Phosphodiesterase, PdeE, from Myxococcus xanthus

Myxococcus xanthus PdeE, an enzyme homologous to class II 3′,5′-cyclic nucleotide phosphodiesterases, hydrolyzed cyclic AMP (cAMP) and cGMP with K(m) values of 12 μM and 25 μM, respectively. A pdeE mutant exhibited delays in fruiting body and spore formation compared with the wild type when cultured...

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Autori principali: Kimura, Yoshio, Yoshimi, Masaaki, Takata, Goro
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133037/
https://ncbi.nlm.nih.gov/pubmed/21317337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01250-10
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