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ZouA, a Putative Relaxase, Is Essential for DNA Amplification in Streptomyces kanamyceticus

Previously, we showed that a 145-kb DNA region, including the entire kanamycin biosynthetic gene cluster (with two kanamycin resistance genes), was tandemly amplified up to 36-fold in an industrial strain of Streptomyces kanamyceticus. Strain improvement had included the use of increased kanamycin r...

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Hlavní autoři: Murakami, Takeshi, Sumida, Naomi, Bibb, Mervyn, Yanai, Koji
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133025/
https://ncbi.nlm.nih.gov/pubmed/21296959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01325-10
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