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ZouA, a Putative Relaxase, Is Essential for DNA Amplification in Streptomyces kanamyceticus
Previously, we showed that a 145-kb DNA region, including the entire kanamycin biosynthetic gene cluster (with two kanamycin resistance genes), was tandemly amplified up to 36-fold in an industrial strain of Streptomyces kanamyceticus. Strain improvement had included the use of increased kanamycin r...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133025/ https://ncbi.nlm.nih.gov/pubmed/21296959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01325-10 |
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