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Unstable Tandem Repeats in Promoters Confer Transcriptional Evolvability

Relative to most regions of the genome, tandemly repeated DNA sequences display a greater propensity to mutate. A search for tandem repeats in the Saccharomyces cerevisiae genome revealed that the nucleosome-free region directly upstream of genes (the promoter region) is enriched in repeats. As many...

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Autors principals: Vinces, Marcelo D., Legendre, Matthieu, Caldara, Marina, Hagihara, Masaki, Verstrepen, Kevin J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132887/
https://ncbi.nlm.nih.gov/pubmed/19478187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1170097
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