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Intragenic tandem repeats generate functional variability

Tandemly repeated DNA sequences are highly dynamic components of genomes1. Most repeats are in intergenic regions, but some are found within coding sequences or pseudogenes2. In humans, expansion of intragenic triplet repeats is associated with various diseases, including Huntington’s chorea and fra...

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Main Authors: Verstrepen, Kevin J., Jansen, An, Lewitter, Fran, Fink, Gerald R.
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462868/
https://ncbi.nlm.nih.gov/pubmed/16086015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1618
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