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Absence of Vasoactive intestinal peptide expression in hematopoietic cells enhances Th1 polarization and anti-viral immunity in mice

Vasoactive intestinal peptide (VIP) induces regulatory dendritic cells (DC) in vitro that inhibit cellular immune responses. We tested the role of physiological levels of VIP on immune responses to murine cytomegalovirus (mCMV) using VIP-knockout (VIP-KO) mice and radiation chimeras engrafted with s...

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Detalhes bibliográficos
Main Authors: Li, Jian-Ming, Southerland, Lauren, Hossain, Mohammad S., Giver, Cynthia R., Wang, Ying, Darlak, Kasia, Harris, Wayne, Waschek, James, Waller, Edmund K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132578/
https://ncbi.nlm.nih.gov/pubmed/21677142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100686
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