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Activation, Immune Polarization, and Graft-versus-Leukemia Activity of Donor T-cells are Regulated by Specific Subsets of Donor Bone Marrow Antigen-Presenting Cells in Allogeneic Hematopoietic Stem Cell Transplantation()

We investigated the roles of specific subsets of donor APCs purified from bone marrow in donor T cell activation and graft-vs-leukemia (GvL) activity in murine models of hemopoietic stem cell transplantation. Lineage(−)CD11c(+) APC precursors were separated from donor bone marrow based on expression...

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Main Authors:	Li, Jian-Ming, Southerland, Lauren T., Lu, Ying, Darlak, Kataryna A., Giver, Cynthia R., McMillin, Douglas W., Harris, Wayne A.C., Jaye, David L., Waller, Edmund K.
格式:	Artigo
語言:	Inglês
出版:	2009
主題:	Article
在線閱讀:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3908652/ https://ncbi.nlm.nih.gov/pubmed/19933853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900155
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Activation, Immune Polarization, and Graft-versus-Leukemia Activity of Donor T-cells are Regulated by Specific Subsets of Donor Bone Marrow Antigen-Presenting Cells in Allogeneic Hematopoietic Stem Cell Transplantation()

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