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Down-regulation of STAT3 expression by vector-based small interfering RNA inhibits pancreatic cancer growth

AIM: To evaluate the effect of RNA interference (RNAi) mediated silence of signal transduction and activation of transcription (STAT)3 on the growth of human pancreatic cancer cells both in vitro and in vivo. METHODS: STAT3 specific shRNA was used to silence the expression of STAT3 in pancreatic can...

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Detalhes bibliográficos
Main Authors: Huang, Chen, Yang, Guang, Jiang, Tao, Cao, Jun, Huang, Ke-Jian, Qiu, Zheng-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132250/
https://ncbi.nlm.nih.gov/pubmed/21799645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v17.i25.2992
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