STAT3 Knockdown Reduces Pancreatic Cancer Cell Invasiveness and Matrix Metalloproteinase-7 Expression in Nude Mice

AIMS: Transducer and activator of transcription-3 (STAT3) plays an important role in tumor cell invasion and metastasis. The aim of the present study was to investigate the effects of STAT3 knockdown in nude mouse xenografts of pancreatic cancer cells and underlying gene expression. METHODS: A STAT3...

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Main Authors: Li, Hai dong, Huang, Chen, Huang, Ke jian, Wu, Wei dong, Jiang, Tao, Cao, Jun, Feng, Zhen zhong, Qiu, Zheng jun
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185063/
https://ncbi.nlm.nih.gov/pubmed/21991388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025941
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