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STAT3 Knockdown Reduces Pancreatic Cancer Cell Invasiveness and Matrix Metalloproteinase-7 Expression in Nude Mice

AIMS: Transducer and activator of transcription-3 (STAT3) plays an important role in tumor cell invasion and metastasis. The aim of the present study was to investigate the effects of STAT3 knockdown in nude mouse xenografts of pancreatic cancer cells and underlying gene expression. METHODS: A STAT3...

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Hlavní autoři: Li, Hai dong, Huang, Chen, Huang, Ke jian, Wu, Wei dong, Jiang, Tao, Cao, Jun, Feng, Zhen zhong, Qiu, Zheng jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185063/
https://ncbi.nlm.nih.gov/pubmed/21991388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025941
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