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Cell-autonomous regulation of hematopoietic stem cell cycling activity by ATP

Extracellular nucleotides regulate many cellular functions through activation of purinergic receptors in the plasma membrane. Here, we show that in hematopoietic stem cell (HSC), ATP is stored in vesicles and released in a calcium-sensitive manner. HSC expresses ATP responsive P2X receptors and in v...

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Detalhes bibliográficos
Main Authors: Casati, A, Frascoli, M, Traggiai, E, Proietti, M, Schenk, U, Grassi, F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131989/
https://ncbi.nlm.nih.gov/pubmed/20798687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.107
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