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Cell cycle regulation in hematopoietic stem cells

Hematopoietic stem cells (HSCs) give rise to all lineages of blood cells. Because HSCs must persist for a lifetime, the balance between their proliferation and quiescence is carefully regulated to ensure blood homeostasis while limiting cellular damage. Cell cycle regulation therefore plays a critic...

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Autors principals: Pietras, Eric M., Warr, Matthew R., Passegué, Emmanuelle
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257565/
https://ncbi.nlm.nih.gov/pubmed/22123859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201102131
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