TAK1 regulates SCF expression to modulate PKBα activity that protects keratinocytes from ROS-induced apoptosis

Dysregulated reactive oxygen species (ROS) generation contributes to many human pathologies, including cancer and diabetes. During normal wound repair, inflammation-induced ROS production must be tightly controlled, but the mechanisms reining their generation remain unclear. Herein, we show that tra...

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Détails bibliographiques
Auteurs principaux: Lam, C R I, Tan, M J, Tan, S H, Tang, M B Y, Cheung, P C F, Tan, N S
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2011
Sujets:
Original Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131962/
https://ncbi.nlm.nih.gov/pubmed/21233843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.182
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