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Nox4-dependent ROS modulation by amino endoperoxides to induce apoptosis in cancer cells

Tumor metastasis is the main cause of death in cancer patients. Anoikis resistance is one critical malefactor of metastatic cancer cells to resist current clinical chemotherapeutic treatments. Although endoperoxide-containing compounds have long been suggested as anticancer drugs, few have been clin...

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Detalhes bibliográficos
Main Authors: Zhu, P, Tong, B MK, Wang, R, Chen, J P, Foo, S, Chong, H C, Wang, X L, Ang, G Y, Chiba, S, Tan, N S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615744/
https://ncbi.nlm.nih.gov/pubmed/23519121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.68
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