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The Beclin 1 network regulates autophagy and apoptosis

Beclin 1, the mammalian orthologue of yeast Atg6, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. It interacts with several cofactors (Atg14L, UVRAG, Bif-1, Rubicon, Ambra1, HMGB1, nPIST,...

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Main Authors: Kang, R, Zeh, H J, Lotze, M T, Tang, D
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131912/
https://ncbi.nlm.nih.gov/pubmed/21311563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.191
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