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Anti-apoptotic effect of hyperglycemia can allow survival of potentially autoreactive T cells
Thymocyte development is a tightly controlled multi-step process involving selective elimination of self-reactive and non-functional T cells by apoptosis. This developmental process depends on signaling by Notch, IL-7 and active glucose metabolism. In this study, we explored the requirement of gluco...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131907/ https://ncbi.nlm.nih.gov/pubmed/21164518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.163 |
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