RASSF7 negatively regulates pro-apoptotic JNK signaling by inhibiting the activity of phosphorylated-MKK7

Members of the Ras-association domain family (RASSF) of proteins influence apoptosis and cell cycling but little is known about the mechanisms. Here, we show that RASSF7 interacts with N-Ras and mitogen-activated protein kinase kinase 7 (MKK7) to negatively regulate c-Jun N-terminal kinase (JNK) sig...

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Bibliographic Details
Main Authors: Takahashi, S, Ebihara, A, Kajiho, H, Kontani, K, Nishina, H, Katada, T
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131899/
https://ncbi.nlm.nih.gov/pubmed/21278800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.137
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