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MAVS-MKK7-JNK2 Defines a Novel Apoptotic Signaling Pathway during Viral Infection

Viral infection induces innate immunity and apoptosis. Apoptosis is an effective means to sacrifice virus-infected host cells and therefore restrict the spread of pathogens. However, the underlying mechanisms of this process are still poorly understood. Here, we show that the mitochondrial antiviral...

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Detalhes bibliográficos
Main Authors: Huang, Yuefeng, Liu, Heng, Li, Senlin, Tang, Yijun, Wei, Bo, Yu, Huansha, Wang, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961361/
https://ncbi.nlm.nih.gov/pubmed/24651600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004020
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