Structure and dynamics of the MKK7–JNK signaling complex

Signaling specificity in the mitogen-activated protein kinase (MAPK) pathways is controlled by disordered domains of the MAPK kinases (MKKs) that specifically bind to their cognate MAPKs via linear docking motifs. MKK7 activates the c-Jun N-terminal kinase (JNK) pathway and is the only MKK containin...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Kragelj, Jaka, Palencia, Andrés, Nanao, Max H., Maurin, Damien, Bouvignies, Guillaume, Blackledge, Martin, Jensen, Malene Ringkjøbing
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2015
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371970/
https://ncbi.nlm.nih.gov/pubmed/25737554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419528112
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