Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial–mesenchymal transition in immortalized prostate cells

A mutation within one allele of the p53 tumor suppressor gene can inactivate the remaining wild-type allele in a dominant-negative manner and in some cases can exert an additional oncogenic activity, known as mutant p53 ‘gain of function' (GOF). To study the role of p53 mutations in prostate ca...

Fuld beskrivelse

Na minha lista:

Bibliografiske detaljer
Main Authors:	Kogan-Sakin, I, Tabach, Y, Buganim, Y, Molchadsky, A, Solomon, H, Madar, S, Kamer, I, Stambolsky, P, Shelly, A, Goldfinger, N, Valsesia-Wittmann, S, Puisieux, A, Zundelevich, A, Gal-Yam, E N, Avivi, C, Barshack, I, Brait, M, Sidransky, D, Domany, E, Rotter, V
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2011
Fag:	Original Paper
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3131887/ https://ncbi.nlm.nih.gov/pubmed/20689556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.94
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!

Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial–mesenchymal transition in immortalized prostate cells

Lignende værker