Variants in or near KITLG, BAK1, DMRT1, and TERT-CLPTM1L predispose to familial testicular germ cell tumour

BACKGROUND: Familial testicular germ cell tumours (TGCTs) and bilateral TGCTs comprise 1–2% and 5% of all TGCTs, respectively, but their genetic basis remains largely unknown. AIM: To investigate the contribution of known testicular cancer risk variants in familial and bilateral TGCTs. METHODS AND R...

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Autori principali: Kratz, Christian P, Han, Summer S, Rosenberg, Philip S, Berndt, Sonja I, Burdett, Laurie, Yeager, Meredith, Korde, Larissa A, Mai, Phuong L, Pfeiffer, Ruth, Greene, Mark H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131696/
https://ncbi.nlm.nih.gov/pubmed/21617256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2011-100001
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