Cyclic AMP-guanine exchange factor activation inhibits JNK-dependent lipopolysaccharide-induced apoptosis in rat hepatocytes

Lipopolysaccharide (LPS) is known to damage hepatocytes by cytokines released from activated Kupffer cells, but the ancillary role of LPS as a direct hepatotoxin is less well characterized. The aim of this study was to determine the direct effect of LPS on hepatocyte viability and the underlying sig...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ponzetti, Kathleen, King, Melissa, Gates, Anna, Anwer, M Sawkat, Webster, Cynthia RL
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2010
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131672/
https://ncbi.nlm.nih.gov/pubmed/21743791
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