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Sulfotyrosine Recognition as Marker for Druggable Sites in the Extracellular Space

Chemokine signaling is a well-known agent of autoimmune disease, HIV infection, and cancer. Drug discovery efforts for these signaling molecules have focused on developing inhibitors targeting their associated G protein-coupled receptors. Recently, we used a structure-based approach directed at the...

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Autori principali: Ziarek, Joshua J., Heroux, Maxime S., Veldkamp, Christopher T., Peterson, Francis C., Volkman, Brian F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Diversity Preservation International (MDPI) 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131587/
https://ncbi.nlm.nih.gov/pubmed/21747703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms12063740
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