FGFR-4 Arg(388) enhances prostate cancer progression via extracellular signal-related kinase and serum response factor signaling

PURPOSE: Increased expression of FGFR-4 and its ligands have been linked to lethal prostate cancer (PCa). Furthermore, a germline polymorphism in the FGFR-4 gene, resulting in arginine at codon 388 (Arg(388)) instead of glycine (Gly(388)), is associated with aggressive disease. The FGFR-4 Arg(388) v...

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Hoofdauteurs: Yu, Wendong, Feng, Shu, Dakhova, Olga, Creighton, Chad J., Cai, Yi, Wang, Jianghua, Li, Rile, Frolov, Anna, Ayala, Gustavo, Ittmann, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131485/
https://ncbi.nlm.nih.gov/pubmed/21622724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2858
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