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FGFR-4 Arg(388) enhances prostate cancer progression via extracellular signal-related kinase and serum response factor signaling
PURPOSE: Increased expression of FGFR-4 and its ligands have been linked to lethal prostate cancer (PCa). Furthermore, a germline polymorphism in the FGFR-4 gene, resulting in arginine at codon 388 (Arg(388)) instead of glycine (Gly(388)), is associated with aggressive disease. The FGFR-4 Arg(388) v...
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| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131485/ https://ncbi.nlm.nih.gov/pubmed/21622724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2858 |
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