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GGAP2/PIKE-A directly activates both the Akt and NF-κB pathways and promotes prostate cancer progression

GGAP2/PIKE-A is a GTP-binding protein which can enhance Akt activity. Increased activation of the AKT and NF-κB pathways have been identified as critical steps in cancer initiation and progression in a variety of human cancers. We have found significantly increased expression GGAP2 in the majority o...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Cai, Yi, Wang, Jianghua, Li, Rile, Ayala, Gustavo, Ittmann, Michael, Liu, Mingyao
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668918/
https://ncbi.nlm.nih.gov/pubmed/19176382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2537
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