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GGAP2/PIKE-A directly activates both the Akt and NF-κB pathways and promotes prostate cancer progression
GGAP2/PIKE-A is a GTP-binding protein which can enhance Akt activity. Increased activation of the AKT and NF-κB pathways have been identified as critical steps in cancer initiation and progression in a variety of human cancers. We have found significantly increased expression GGAP2 in the majority o...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668918/ https://ncbi.nlm.nih.gov/pubmed/19176382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2537 |
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