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Non-canonical β-catenin degradation mediates reactive oxygen species-induced epidermal cell death

β-catenin is constantly degraded through the ubiquitin-proteasomal pathway. We here report that a different type of β-catenin degradation is causally involved in epidermal cell death. We observed that reactive oxygen species (ROS) caused β-catenin degradation in the epidermal cells through a caspase...

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Bibliografiske detaljer
Main Authors: Omori, Emily, Matsumoto, Kunihiro, Ninomiya-Tsuji, Jun
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131442/
https://ncbi.nlm.nih.gov/pubmed/21383695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.49
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