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Role of IL-1 receptor-associated kinase-M (IRAK-M) in priming of immune and inflammatory responses by nitrogen bisphosphonates

Nitrogen bisphosphonates (NBPs) are commonly prescribed for osteoporosis but have also been found to induce inflammatory reactions and to delay the progression of breast cancer. The inflammatory and anticancer effects of the NBPs might be associated with an ability to modulate innate immune signalin...

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Détails bibliographiques
Auteurs principaux: Norton, John T., Hayashi, Tomoko, Crain, Brian, Corr, Maripat, Carson, Dennis A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131380/
https://ncbi.nlm.nih.gov/pubmed/21690387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107899108
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