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Cutting Edge: Nitrogen bisphosphonate-induced inflammation is dependent upon mast cells and IL-1
Nitrogen containing bisphosphonates (NBPs) are taken by millions for bone disorders but may cause serious inflammatory reactions. Here, we utilized a murine peritonitis model to characterize the inflammatory mechanisms of these agents. At dosages comparable to those used in humans, injection of NBPs...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311728/ https://ncbi.nlm.nih.gov/pubmed/22387558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100830 |
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