Acute hepatitis A virus infection is associated with a limited type I interferon response and persistence of intrahepatic viral RNA

Hepatitis A virus (HAV) is an hepatotropic human picornavirus that is associated only with acute infection. Its pathogenesis is not well understood because there are few studies in animal models using modern methodologies. We characterized HAV infections in three chimpanzees, quantifying viral RNA b...

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Hauptverfasser: Lanford, Robert E., Feng, Zongdi, Chavez, Deborah, Guerra, Bernadette, Brasky, Kathleen M., Zhou, Yan, Yamane, Daisuke, Perelson, Alan S., Walker, Christopher M., Lemon, Stanley M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131353/
https://ncbi.nlm.nih.gov/pubmed/21690403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101939108
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