Antiviral activity and host gene induction by tamarin and marmoset interferon-α and interferon-γ in the GBV-B primary hepatocyte culture model

GBV-B induces hepatitis in tamarins and marmosets and is a surrogate model for HCV infections. Here, we cloned and characterized the antiviral activity of tamarin and marmoset interferon (IFN)α and IFNγ. Potent antiviral activity was observed for tamarin and marmoset IFNα in primary hepatocyte cultu...

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Hlavní autoři: Chavez, Deborah, Guerra, Bernadette, Lanford, Robert E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753388/
https://ncbi.nlm.nih.gov/pubmed/19501869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.05.005
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