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PEG with Observable Shedding

A novel FRET-bearing poly(ethylene glycol) (PEG) conjugate fluoresces at 520 nm when it is cleaved off from nanoparticles (NPs). When the NPs were targeted to cancer cell lines, the reducing redox of the endosomal compartment caused disulfide bond cleavage and shedding of the PEG layer. The fluoresc...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Gao, Weiwei, Langer, Robert, Farokhzad, Omid C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131112/
https://ncbi.nlm.nih.gov/pubmed/20677297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201001868
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