Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

SHANK3 is a synaptic scaffolding protein enriched in the postsynaptic density (PSD) of excitatory synapses. Small microdeletions and point mutations in SHANK3 have been identified in a small subgroup of individuals with autism spectrum disorder (ASD) and intellectual disability. SHANK3 also plays a...

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Main Authors: Wang, Xiaoming, McCoy, Portia A., Rodriguiz, Ramona M., Pan, Yanzhen, Je, H. Shawn, Roberts, Adam C., Kim, Caroline J., Berrios, Janet, Colvin, Jennifer S., Bousquet-Moore, Danielle, Lorenzo, Isabel, Wu, Gangyi, Weinberg, Richard J., Ehlers, Michael D., Philpot, Benjamin D., Beaudet, Arthur L., Wetsel, William C., Jiang, Yong-hui
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131048/
https://ncbi.nlm.nih.gov/pubmed/21558424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr212
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