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Internal deletion compromises the stability of dystrophin
Duchenne muscular dystrophy (DMD) is a deadly and common childhood disease caused by mutations that disrupt dystrophin protein expression. Several miniaturized dystrophin/utrophin constructs are utilized for gene therapy, and while these constructs have shown promise in mouse models, the functional...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131041/ https://ncbi.nlm.nih.gov/pubmed/21558423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr199 |
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