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NanoRNAs prime transcription initiation in vivo

It is often presumed that, in vivo, the initiation of RNA synthesis by DNA-dependent RNA polymerases occurs using NTPs alone. Here, using the model Gram-negative bacterium Pseudomonas aeruginosa, we demonstrate that depletion of the small-RNA-specific exonuclease, Oligoribonuclease, causes the accum...

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Détails bibliographiques
Auteurs principaux: Goldman, Seth R., Sharp, Josh S., Vvedenskaya, Irina O., Livny, Jonathan, Dove, Simon L., Nickels, Bryce E.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130991/
https://ncbi.nlm.nih.gov/pubmed/21700226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.06.005
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