Transforming growth factor-β2 increases extracellular matrix proteins in optic nerve head cells via activation of the Smad signaling pathway

PURPOSE: Transforming growth factor-β2 (TGF-β2) is associated with glaucomatous neuropathy, primarily via the increased synthesis and secretion of extracellular matrix (ECM) proteins and remodeling of the optic nerve head (ONH). Here, we investigated the signaling pathways used by TGF-β2 to stimulat...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Zode, Gulab S., Sethi, Anirudh, Brun-Zinkernagel, Anne-Marie, Chang, I-Fen, Clark, Abbot F., Wordinger, Robert J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Molecular Vision 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130727/
https://ncbi.nlm.nih.gov/pubmed/21738403
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares