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Prophylactic neuroprotection against stroke: low-dose, prolonged treatment with deferoxamine or deferasirox establishes prolonged neuroprotection independent of HIF-1 function
Prophylactic neuroprotection against stroke could reduce stroke burden in thousands of patients at high risk of stroke, including those with recent transient ischemic attacks (TIAs). Prolyl hydroxylase inhibitors (PHIs), such as deferoxamine (DFO), reduce stroke volume when administered at high dose...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3130314/ https://ncbi.nlm.nih.gov/pubmed/21245873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.230 |
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