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Prophylactic neuroprotection against stroke: low-dose, prolonged treatment with deferoxamine or deferasirox establishes prolonged neuroprotection independent of HIF-1 function

Prophylactic neuroprotection against stroke could reduce stroke burden in thousands of patients at high risk of stroke, including those with recent transient ischemic attacks (TIAs). Prolyl hydroxylase inhibitors (PHIs), such as deferoxamine (DFO), reduce stroke volume when administered at high dose...

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Sonraí Bibleagrafaíochta
Main Authors: Zhao, Yanxin, Rempe, David A
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130314/
https://ncbi.nlm.nih.gov/pubmed/21245873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.230
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