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Reconstitution and characterization of the unconventional splicing of XBP1u mRNA in vitro
Upon endoplasmic reticulum (ER) stress, mammalian cells induce the synthesis of a transcriptional activator XBP1s to alleviate the stress. Under unstressed conditions, the messenger RNA (mRNA) for XBP1s exists in the cytosol as an unspliced precursor form, XBP1u mRNA. Thus, its intron must be remove...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3130286/ https://ncbi.nlm.nih.gov/pubmed/21398633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr132 |
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