Reconstitution and characterization of the unconventional splicing of XBP1u mRNA in vitro

Upon endoplasmic reticulum (ER) stress, mammalian cells induce the synthesis of a transcriptional activator XBP1s to alleviate the stress. Under unstressed conditions, the messenger RNA (mRNA) for XBP1s exists in the cytosol as an unspliced precursor form, XBP1u mRNA. Thus, its intron must be remove...

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Dettagli Bibliografici
Autori principali: Shinya, Sayoko, Kadokura, Hiroshi, Imagawa, Yusuke, Inoue, Michihiro, Yanagitani, Kota, Kohno, Kenji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
RNA
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130286/
https://ncbi.nlm.nih.gov/pubmed/21398633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr132
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