PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms

Post-translational poly(ADP-ribosyl)ation has diverse essential functions in the cellular response to DNA damage as it contributes to avid DNA damage detection and assembly of the cellular repair machinery but extensive modification eventually also induces cell death. While there are 17 human poly(A...

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Main Authors: Mortusewicz, Oliver, Fouquerel, Elise, Amé, Jean-Christophe, Leonhardt, Heinrich, Schreiber, Valérie
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130271/
https://ncbi.nlm.nih.gov/pubmed/21398629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr099
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