Llwytho...

Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells

Genome integrity is constantly threatened by DNA lesions arising from numerous exogenous and endogenous sources. Survival depends on immediate recognition of these lesions and rapid recruitment of repair factors. Using laser microirradiation and live cell microscopy we found that the DNA-damage depe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mortusewicz, Oliver, Amé, Jean-Christophe, Schreiber, Valérie, Leonhardt, Heinrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190722/
https://ncbi.nlm.nih.gov/pubmed/17982172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm933
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