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Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation
Canonical Wnt-signalling has been implicated in mouse and human embryonic stem cell (ESC) maintenance, however its requirement is controversial. β-catenin is the key component in this highly conserved Wnt pathway, acting as a transcriptional transactivator. Yet, β-catenin has additional roles at the...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3130149/ https://ncbi.nlm.nih.gov/pubmed/21685890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2260 |
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