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T-bet-mediated differentiation of the activated CD8(+) T cell

The T-box transcription factor, T-bet promotes the differentiation of short-lived effector CD8(+) T cells at the expense of central memory cells. How T-bet mediates these effects, and whether they are directly caused by T-bet alone are unknown, because expression of T-bet requires stimulation of the...

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Detalhes bibliográficos
Main Authors: Yeo, Crystal J J, Fearon, Douglas T
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130140/
https://ncbi.nlm.nih.gov/pubmed/21182077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040873
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