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Decreased aortic diameter and compliance precedes blood pressure increases in postnatal development of elastin-insufficient mice

Increased arterial stiffness and blood pressure are characteristic of humans and adult mice with reduced elastin levels caused by aging or genetic disease. Direct associations have been shown between increased arterial stiffness and hypertension in humans, but it is not known whether changes in mech...

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Autors principals: Le, Victoria P., Knutsen, Russell H., Mecham, Robert P., Wagenseil, Jessica E.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129922/
https://ncbi.nlm.nih.gov/pubmed/21536846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00119.2011
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